Playfair Display is a sophisticated font with tall, imposing letters. It’s ideal for titles, headlines and short blocks of copy – like a product description.
Playfair Display is a sophisticated font with tall, imposing letters. It’s ideal for titles, headlines and short blocks of copy – like a product description.
Playfair Display is a sophisticated font with tall, imposing letters. It’s ideal for titles, headlines and short blocks of copy – like a product description.
Playfair Display is a sophisticated font with tall, imposing letters. It’s ideal for titles, headlines and short blocks of copy – like a product description.
Playfair Display is a sophisticated font with tall, imposing letters. It’s ideal for titles, headlines and short blocks of copy – like a product description.
Playfair Display is a sophisticated font with tall, imposing letters. It’s ideal for titles, headlines and short blocks of copy – like a product description.
The versatile, non-pharmacologic choice for cervical ripening1,2
DILAPAN-S TODAY
for planned inductions tomorrow
Gentle enough for her to sleep through, predictable enough for you to schedule around3
HOW DILAPAN S WORKS
-
DILAPAN-S IS A NON-PHARMACOLOGIC, MECHANICAL CERVICAL DILATOR
designed for gentle, safe, and predictable cervical ripening in the induction of labor1-4
It is composed of Aquacryl®, a firm, synthetic, patented hydrogel that increases in volume by absorbing fluids.2
-
Each rod swells to several times its original diameter through absorption of moisture from the cervix.
-
Approximately 80% of rod swelling occurs within the first 4-6 hours after insertion.
-
In a single procedure typically 3 to 5 rods are inserted, with the rods inserted one at a time.4,6
0 Hours
Dilapan-S
at insertion
2 Hours
4 Hours
8 Hours
12-24 Hours
Dilapan-S
at removal
Each 4mm rod can expand up to ~15mm in diameter1,2
Make Dilapan-S your first-choice cervical ripening agent
Watch the Insertion and Removal Video
MULTIPLE MODES OF ACTION
After insertion, Dilapan-S initiates a cascade of biophysical, mechanical, and physiological changes in the cervical tissue that continue until removal of the rods.2,5
BIOPHYSICAL
-
Dilapan-S rods are inserted into the cervical canal, where they absorb moisture from the cervix
-
Cervical tissue softens as it dehydrates
MECHANICAL
-
Dilapan-S rods expand, exerting controlled radial pressure on the cervical canal, which dilates the cervix
PHYSIOLOGICAL
-
Stretching of the cervical tissue promotes the release of local endogenous prostaglandins
-
Local prostaglandins initiate collagen degradation and cervical softening and ripening
With Dilapan-S the cervix gradually and predictably softens and dilates, preparing the mother for the next step in induction of labor.2,5
CONSISTENT CLINICAL EFFICACY
DILAPAN-S® PREPARES WOMEN FOR SUCCESSFUL VAGINAL DELIVERY
In 3 clinical studies, Dilapan-S achieved a vaginal delivery rate ranging from 70% to 81%.3,4,6*
Percentage
100%
90%
80%
70%
60%
50%
40%
30%
20%
10%
0%
Overall vaginal delivery rate*
(310/444)
(169/208)
81
%
(46/61)
75
%
Gupta 20184*
Saad 20193
Vik 20146
*Includes ventouse/vacuum and/or forcep assisted delivery.
70
%
DILAPAN-S® ACHIEVES RELIABLE CERVICAL RIPENING SUCCESS
In 2 clinical studies, the majority of women who used Dilapan-S did not require additional cervical ripening.3,4
93
%
%
87
(N=444)
Gupta 20184
(N=208)
Saad 20193
DILAPAN-S® PREPARES WOMEN FOR SUCCESSFUL VAGINAL DELIVERY
In 4 clinical studies, Dilapan-S achieved a vaginal delivery rate ranging from 52% to 75% among vaginal birth after cesarean (VBAC) populations.4,6,8,9**
Percentage
100%
90%
80%
70%
60%
50%
40%
30%
20%
10%
0%
VBAC delivery rate**
Gupta 20184
Vik 20146
Maier 20158
Maier 20189
**Includes women with a history of previous cesarean delivery.
52
%
65
%
75
%
55
%
STRONG SAFETY PROFILE
NO PHARMACOLOGICALLY ACTIVE SUBSTANCES
Dilapan-S® is free from agents and attributes associated with other cervical ripening methods.1,2,5
NO UTERINE TACHYSYSTOLE
In 2 large studies representing a total of 640 women (including VBAC patients) using Dilapan-S,
there were no cases of uterine tachysystole related to Dilapan-S use during cervical ripening.2,6
LOW RATE OF ADVERSE EVENTS
Of 444 women treated with Dilapan-S during induction of labor4:
-
<1% reported cramping or pain
-
2.7% experienced bleeding during Dilapan-S insertion or removal
-
No maternal infections (including chorioamnionitis, urinary tract infections, endometritis, and wound infections) were attributed to use of Dilapan-S by the investigating physicians
-
No serious adverse neonatal outcomes were attributed to use of Dilapan-S
SAFE FOR MULTIPLE PATIENT TYPES3,4,9
NULLIPAROUS
MULTIPAROUS
PREECLAMPSIA
TOLAC
DIABETES
OBESITY
POST-DATES PREGNANCIES (>41 WEEKS)
OLIGOHYDRAMNIOS
PRE-LABOR RUPTURE
OF MEMBRANES
HIGH PATIENT COMFORT
%
OVER
80
of patients were
able to sleep during
cervical ripening6
WITH DILAPAN-S®, YOUR PATIENTS ARE FREE TO3,6:
-
Ambulate without uncomfortable tubing
-
Shower, use the toilet, and perform other normal daily activities*
-
Sleep while their cervix ripens gently and gradually